List of non sedating

The first three nonbenzodiazepine drugs to enter the market were the "Z-drugs", zopiclone, zolpidem and zaleplon.

These three drugs are all sedatives used exclusively for the treatment of mild insomnia.

Nonbenzodiazepine pharmacodynamics are almost entirely the same as benzodiazepine drugs and therefore employ similar benefits, side-effects, and risks.

However, nonbenzodiazepines have dissimilar or entirely different chemical structures and are therefore unrelated to benzodiazepines on a molecular level.

The nonbenzodiazepines are positive allosteric modulators of the GABA-A receptor.